The smart Trick of ceesdekker That No One is Discussing
The smart Trick of ceesdekker That No One is Discussing
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‘Certainly, that is certainly about ideal. I seek out a Actual physical understanding of biological devices inside a bottom-up way. I feel you could distinguish 3 strains of research in my group for the time being. The primary fears chromosome structure: How can you get yourself a metre-extensive DNA polymer folded and organised in such a microscopic cell? We've got formulated visualisation procedures that permit us to review how, one example is, SMC proteins loop DNA (online video on Youtube) in order to Develop up chromosomes.
It absolutely was only within the nineteen nineties although, when nanotechnology experienced advanced into a amount in which one molecules might be manipulated, that the 1st experimental gadgets started to appear.
, Groningen researchers present the results of their efforts to produce labs far more sustainable and supply methods for other labs.
2007, first true-time detection of strand Trade in homologous recombination by RecA; discovery of a minimal persistence duration of finishes of microtubules; and resolved the mechanism of biosensing with carbon nanotubes
2012, discovery that nucleoid occlusion underlies the precision of bacterial cell division; and initially ever review in the dynamics DNA supercoils and the invention of supercoil hopping
Experimental period diagram of negatively supercoiled DNA measured by magnetic tweezers and fluorescence,
You are a Christian. If you could potentially make this type of artificial cell, would you be a person phase nearer to God, or would the position of God have diminished relatively yet again?
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Resolving the stage size in condensin-driven DNA loop extrusion identifies ATP binding as the step-building process
An built-in microfluidic platform for quantifying drug permeation across biomimetic vesicle membranes
Mother nature Physics thanks the nameless reviewers for their contribution to the peer critique of this do the job.
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2004, discovery of new physics in translocation of DNA by nanopores; very first experimental study of ions conduction in nanofluidic channels; initially electrochemistry with personal one-wall carbon nanotubes; STM detection and control of phonons in carbon nanotubes; first electrical docking of microtubules on kinesin-coated nanostructures; initially biophysics characterization in the mechanical properties of double-stranded RNA; and 1st single-molecule review of DNA translocation by a restriction-modification enzyme.